BDBM50068318 CHEMBL145311::N-[9,10-Dioxo-8-(3-(N,N-diethyl-N-methyl-propionylamino)-9,10-dihydro-anthracen-1-yl]-3-(N,N-diethyl-N-methyl)-propionamide; diiodide
SMILES: CC[N+](C)(CC)CCC(=O)Nc1cccc2C(=O)c3cccc(NC(=O)CC[N+](C)(CC)CC)c3C(=O)c12
InChI Key: InChIKey=IDPQGAPTLMPRDI-UHFFFAOYSA-P
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50068318 (CHEMBL145311 | N-[9,10-Dioxo-8-(3-(N,N-diethyl-N-m...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibitory activity of telomerase was measured using the TRAP assay. | J Med Chem 41: 4873-84 (1998) Article DOI: 10.1021/jm981067o BindingDB Entry DOI: 10.7270/Q2WW7GSD | |||||||||||
More data for this Ligand-Target Pair |