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BDBM50068390 CHEMBL3402351

SMILES: CNCCCC(=O)N1N=C(SC11CCOc2ccccc12)c1cc(F)ccc1F

InChI Key: InChIKey=KSHNRZSDLOVYHT-UHFFFAOYNA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50068390   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kinesin-like protein 1


(Homo sapiens (Human))
BDBM50068390
PNG
(CHEMBL3402351)
Show SMILES CNCCCC(=O)N1N=C(SC11CCOc2ccccc12)c1cc(F)ccc1F |c:8|
Show InChI InChI=1/C21H21F2N3O2S/c1-24-11-4-7-19(27)26-21(10-12-28-18-6-3-2-5-16(18)21)29-20(25-26)15-13-14(22)8-9-17(15)23/h2-3,5-6,8-9,13,24H,4,7,10-12H2,1H3
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MMDB

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PC cid
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Article
PubMed
n/an/an/an/a 367n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of KSP in human HCT116 cells assessed as phos-histone H3 level by immunofluorescent assay


Bioorg Med Chem 23: 2424-34 (2015)


Article DOI: 10.1016/j.bmc.2015.03.052
More data for this
Ligand-Target Pair