null

SMILES: CC(C)N1CN(C)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O

InChI Key: InChIKey=KKTPGSBDSZRGAT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50068518   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50068518 (8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-isopropyl-1-...) Show SMILES CC(C)N1CN(C)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O Show InChI InChI=1S/C21H30FN3O2/c1-16(2)25-15-23(3)21(20(25)27)10-13-24(14-11-21)12-4-5-19(26)17-6-8-18(22)9-7-17/h6-9,16H,4-5,10-15H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against rat 5-hydroxytryptamine 2A receptor in NIH3T3 cells.				J Med Chem 41: 5084-93 (1999) Article DOI: 10.1021/jm980452a BindingDB Entry DOI: 10.7270/Q2CZ369B
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50068518 (8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-isopropyl-1-...) Show SMILES CC(C)N1CN(C)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O Show InChI InChI=1S/C21H30FN3O2/c1-16(2)25-15-23(3)21(20(25)27)10-13-24(14-11-21)12-4-5-19(26)17-6-8-18(22)9-7-17/h6-9,16H,4-5,10-15H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against rat Dopamine receptor D2.				J Med Chem 41: 5084-93 (1999) Article DOI: 10.1021/jm980452a BindingDB Entry DOI: 10.7270/Q2CZ369B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50068518 (8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-isopropyl-1-...) Show SMILES CC(C)N1CN(C)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O Show InChI InChI=1S/C21H30FN3O2/c1-16(2)25-15-23(3)21(20(25)27)10-13-24(14-11-21)12-4-5-19(26)17-6-8-18(22)9-7-17/h6-9,16H,4-5,10-15H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against rat 5-hydroxytryptamine 1A receptor in CHO cells.				J Med Chem 41: 5084-93 (1999) Article DOI: 10.1021/jm980452a BindingDB Entry DOI: 10.7270/Q2CZ369B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50068518 (8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-isopropyl-1-...) Show SMILES CC(C)N1CN(C)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O Show InChI InChI=1S/C21H30FN3O2/c1-16(2)25-15-23(3)21(20(25)27)10-13-24(14-11-21)12-4-5-19(26)17-6-8-18(22)9-7-17/h6-9,16H,4-5,10-15H2,1-3H3	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against rat 5-hydroxytryptamine 2C receptor in A-9 cells.				J Med Chem 41: 5084-93 (1999) Article DOI: 10.1021/jm980452a BindingDB Entry DOI: 10.7270/Q2CZ369B
					More data for this Ligand-Target Pair