BDBM50068850 (R)-2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-2-cyclopentyl-N-hydroxy-acetamide::CHEMBL353451

SMILES: COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)[C@H](C1CCCC1)C(=O)NO

InChI Key: InChIKey=GVDQXCDJMFQLTH-HXUWFJFHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50068850   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase 12 (Mus musculus)	BDBM50068850 ((R)-2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-2...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)[C@H](C1CCCC1)C(=O)NO Show InChI InChI=1S/C21H26N2O5S/c1-28-18-11-13-19(14-12-18)29(26,27)23(15-16-7-3-2-4-8-16)20(21(24)22-25)17-9-5-6-10-17/h2-4,7-8,11-14,17,20,25H,5-6,9-10,15H2,1H3,(H,22,24)/t20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrate				Bioorg Med Chem Lett 8: 897-902 (1999) BindingDB Entry DOI: 10.7270/Q2NP24ZC
					More data for this Ligand-Target Pair