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BDBM50069456 1-Methyl-1H-pyrrole-2-carboxylic acid (7-bromo-2,3-dioxo-1,2,3,4-tetrahydro-quinoxalin-5-ylmethyl)-amide::CHEMBL434644

SMILES: Cn1cccc1C(=O)NCc1cc(Br)cc2[nH]c(=O)c(=O)[nH]c12

InChI Key: InChIKey=VLQYYHZLTPAQRH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50069456   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50069456
PNG
(1-Methyl-1H-pyrrole-2-carboxylic acid (7-bromo-2,3...)
Show SMILES Cn1cccc1C(=O)NCc1cc(Br)cc2[nH]c(=O)c(=O)[nH]c12
Show InChI InChI=1S/C15H13BrN4O3/c1-20-4-2-3-11(20)13(21)17-7-8-5-9(16)6-10-12(8)19-15(23)14(22)18-10/h2-6H,7H2,1H3,(H,17,21)(H,18,22)(H,19,23)
PDB

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PC sid
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PubMed
n/an/a 20n/an/an/an/an/an/a



Novartis Pharma AG

Curated by ChEMBL


Assay Description
In vitro binding assay for the displacement of [3H]MDL-105519 from the glycine-site of NMDA receptors

Bioorg Med Chem Lett 8: 493-8 (1999)


BindingDB Entry DOI: 10.7270/Q29G5NBG
More data for this
Ligand-Target Pair