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BDBM50069459 CHEMBL413125::Thiophene-3-carboxylic acid (7-bromo-2,3-dioxo-1,2,3,4-tetrahydro-quinoxalin-5-ylmethyl)-amide

SMILES: Brc1cc(CNC(=O)c2ccsc2)c2[nH]c(=O)c(=O)[nH]c2c1

InChI Key: InChIKey=LNMWESMZEHGRPV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50069459   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50069459
PNG
(CHEMBL413125 | Thiophene-3-carboxylic acid (7-brom...)
Show SMILES Brc1cc(CNC(=O)c2ccsc2)c2[nH]c(=O)c(=O)[nH]c2c1
Show InChI InChI=1S/C14H10BrN3O3S/c15-9-3-8(5-16-12(19)7-1-2-22-6-7)11-10(4-9)17-13(20)14(21)18-11/h1-4,6H,5H2,(H,16,19)(H,17,20)(H,18,21)
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PubMed
n/an/a 10n/an/an/an/an/an/a



Novartis Pharma AG

Curated by ChEMBL


Assay Description
In vitro binding assay for the displacement of [3H]MDL-105519 from the glycine-site of NMDA receptors

Bioorg Med Chem Lett 8: 493-8 (1999)


BindingDB Entry DOI: 10.7270/Q29G5NBG
More data for this
Ligand-Target Pair