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BDBM50069460 CHEMBL144365::N-(7-Nitro-2,3-dioxo-1,2,3,4-tetrahydro-quinoxalin-5-ylmethyl)-2-phenyl-acetamide

SMILES: [O-][N+](=O)c1cc(CNC(=O)Cc2ccccc2)c2[nH]c(=O)c(=[OH+])[n-]c2c1

InChI Key: InChIKey=BAWQNURHTFUYCQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50069460   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50069460
PNG
(CHEMBL144365 | N-(7-Nitro-2,3-dioxo-1,2,3,4-tetrah...)
Show SMILES [O-][N+](=O)c1cc(CNC(=O)Cc2ccccc2)c2[nH]c(=O)c(=[OH+])[n-]c2c1
Show InChI InChI=1S/C17H14N4O5/c22-14(6-10-4-2-1-3-5-10)18-9-11-7-12(21(25)26)8-13-15(11)20-17(24)16(23)19-13/h1-5,7-8H,6,9H2,(H3,18,19,20,22,23,24)
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 40n/an/an/an/an/an/a



Novartis Pharma AG

Curated by ChEMBL


Assay Description
In vitro binding assay for the displacement of [3H]MDL-105519 from the glycine-site of NMDA receptors

Bioorg Med Chem Lett 8: 493-8 (1999)


BindingDB Entry DOI: 10.7270/Q29G5NBG
More data for this
Ligand-Target Pair