BDBM50069470 CHEMBL145606::N-(7-Bromo-2,3-dioxo-1,2,3,4-tetrahydro-quinoxalin-5-ylmethyl)-2-(3-methoxy-phenyl)-acetamide

SMILES: COc1cccc(CC(=O)NCc2cc(Br)cc3[nH]c(=O)c(=O)[nH]c23)c1

InChI Key: InChIKey=OPCFSDCUKYIAHK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50069470   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50069470 (CHEMBL145606 | N-(7-Bromo-2,3-dioxo-1,2,3,4-tetrah...) Show SMILES COc1cccc(CC(=O)NCc2cc(Br)cc3[nH]c(=O)c(=O)[nH]c23)c1 Show InChI InChI=1S/C18H16BrN3O4/c1-26-13-4-2-3-10(5-13)6-15(23)20-9-11-7-12(19)8-14-16(11)22-18(25)17(24)21-14/h2-5,7-8H,6,9H2,1H3,(H,20,23)(H,21,24)(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description In vitro binding assay for the displacement of [3H]MDL-105519 from the glycine-site of NMDA receptors				Bioorg Med Chem Lett 8: 493-8 (1999) BindingDB Entry DOI: 10.7270/Q29G5NBG
					More data for this Ligand-Target Pair