BDBM50069478 3-Methyl-thiophene-2-carboxylic acid (7-bromo-2,3-dioxo-1,2,3,4-tetrahydro-quinoxalin-5-ylmethyl)-amide::CHEMBL358362

SMILES: Cc1ccsc1C(=O)NCc1cc(Br)cc2[nH]c(=O)c(=O)[nH]c12

InChI Key: InChIKey=KCYVKJSNFMNELK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50069478   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50069478 (3-Methyl-thiophene-2-carboxylic acid (7-bromo-2,3-...) Show SMILES Cc1ccsc1C(=O)NCc1cc(Br)cc2[nH]c(=O)c(=O)[nH]c12 Show InChI InChI=1S/C15H12BrN3O3S/c1-7-2-3-23-12(7)13(20)17-6-8-4-9(16)5-10-11(8)19-15(22)14(21)18-10/h2-5H,6H2,1H3,(H,17,20)(H,18,21)(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description In vitro binding assay for the displacement of [3H]MDL-105519 from the glycine-site of NMDA receptors				Bioorg Med Chem Lett 8: 493-8 (1999) BindingDB Entry DOI: 10.7270/Q29G5NBG
					More data for this Ligand-Target Pair