BDBM50069582 (R)-N*1*-((S)-1-Benzylcarbamoyl-2-phenyl-ethyl)-N*4*-hydroxy-2-isobutyl-succinamide::CHEMBL96654

SMILES: CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCc1ccccc1

InChI Key: InChIKey=RZIOSGXPNNBJBD-RTWAWAEBSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50069582   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Immunoglobulin epsilon Fc receptor (Homo sapiens (Human))	BDBM50069582 ((R)-N*1*-((S)-1-Benzylcarbamoyl-2-phenyl-ethyl)-N*...) Show SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C24H31N3O4/c1-17(2)13-20(15-22(28)27-31)23(29)26-21(14-18-9-5-3-6-10-18)24(30)25-16-19-11-7-4-8-12-19/h3-12,17,20-21,31H,13-16H2,1-2H3,(H,25,30)(H,26,29)(H,27,28)/t20-,21+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line)				Bioorg Med Chem Lett 8: 23-8 (1999) BindingDB Entry DOI: 10.7270/Q2ZK5FT6
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50069582 ((R)-N*1*-((S)-1-Benzylcarbamoyl-2-phenyl-ethyl)-N*...) Show SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C24H31N3O4/c1-17(2)13-20(15-22(28)27-31)23(29)26-21(14-18-9-5-3-6-10-18)24(30)25-16-19-11-7-4-8-12-19/h3-12,17,20-21,31H,13-16H2,1-2H3,(H,25,30)(H,26,29)(H,27,28)/t20-,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity of the compound towards human recombinant fibroblast collagenase				Bioorg Med Chem Lett 8: 29-34 (1999) BindingDB Entry DOI: 10.7270/Q2TT4Q3W
					More data for this Ligand-Target Pair
Immunoglobulin epsilon Fc receptor (Homo sapiens (Human))	BDBM50069582 ((R)-N*1*-((S)-1-Benzylcarbamoyl-2-phenyl-ethyl)-N*...) Show SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C24H31N3O4/c1-17(2)13-20(15-22(28)27-31)23(29)26-21(14-18-9-5-3-6-10-18)24(30)25-16-19-11-7-4-8-12-19/h3-12,17,20-21,31H,13-16H2,1-2H3,(H,25,30)(H,26,29)(H,27,28)/t20-,21+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells				Bioorg Med Chem Lett 8: 29-34 (1999) BindingDB Entry DOI: 10.7270/Q2TT4Q3W
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50069582 ((R)-N*1*-((S)-1-Benzylcarbamoyl-2-phenyl-ethyl)-N*...) Show SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C24H31N3O4/c1-17(2)13-20(15-22(28)27-31)23(29)26-21(14-18-9-5-3-6-10-18)24(30)25-16-19-11-7-4-8-12-19/h3-12,17,20-21,31H,13-16H2,1-2H3,(H,25,30)(H,26,29)(H,27,28)/t20-,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity towards human recombinant fibroblast collagenase				Bioorg Med Chem Lett 8: 23-8 (1999) BindingDB Entry DOI: 10.7270/Q2ZK5FT6
					More data for this Ligand-Target Pair