BDBM50069598 (2R,3S)-N*4*-((S)-1-Carbamoyl-2-phenyl-ethyl)-2-{2-(4-chloro-phenyl)-2-[(E)-hydroxyimino]-ethylsulfanylmethyl}-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL326148

SMILES: CC(C)C[C@H]([C@H](CSCC(N=O)c1ccc(Cl)cc1)C(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key: InChIKey=NDALNAHQTWQQRJ-ZFSMBLLKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50069598   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Homo sapiens (Human))	BDBM50069598 ((2R,3S)-N*4*-((S)-1-Carbamoyl-2-phenyl-ethyl)-2-{2...) Show SMILES CC(C)C[C@H]([C@H](CSCC(N=O)c1ccc(Cl)cc1)C(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C26H33ClN4O5S/c1-16(2)12-20(25(33)29-22(24(28)32)13-17-6-4-3-5-7-17)21(26(34)31-36)14-37-15-23(30-35)18-8-10-19(27)11-9-18/h3-11,16,20-23,36H,12-15H2,1-2H3,(H2,28,32)(H,29,33)(H,31,34)/t20-,21+,22+,23?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity of the compound towards human recombinant fibroblast collagenase				Bioorg Med Chem Lett 8: 29-34 (1999) BindingDB Entry DOI: 10.7270/Q2TT4Q3W
					More data for this Ligand-Target Pair
Immunoglobulin epsilon Fc receptor (Homo sapiens (Human))	BDBM50069598 ((2R,3S)-N*4*-((S)-1-Carbamoyl-2-phenyl-ethyl)-2-{2...) Show SMILES CC(C)C[C@H]([C@H](CSCC(N=O)c1ccc(Cl)cc1)C(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C26H33ClN4O5S/c1-16(2)12-20(25(33)29-22(24(28)32)13-17-6-4-3-5-7-17)21(26(34)31-36)14-37-15-23(30-35)18-8-10-19(27)11-9-18/h3-11,16,20-23,36H,12-15H2,1-2H3,(H2,28,32)(H,29,33)(H,31,34)/t20-,21+,22+,23?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells				Bioorg Med Chem Lett 8: 29-34 (1999) BindingDB Entry DOI: 10.7270/Q2TT4Q3W
					More data for this Ligand-Target Pair