BDBM50069633 CHEMBL3402541

SMILES: Cc1cnc(C(Cc2ccccc2)NS(=O)(=O)c2ccc(Cl)cc2)n1C

InChI Key: InChIKey=LYFKGSMALVXRKQ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50069633   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50069633 (CHEMBL3402541) Show SMILES Cc1cnc(C(Cc2ccccc2)NS(=O)(=O)c2ccc(Cl)cc2)n1C Show InChI InChI=1S/C19H20ClN3O2S/c1-14-13-21-19(23(14)2)18(12-15-6-4-3-5-7-15)22-26(24,25)17-10-8-16(20)9-11-17/h3-11,13,18,22H,12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.61E+3	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity against S1P1R in human U2OS cells expressing beta-arrestin/green fluorescent protein assessed as effect on S1P-induced beta-arres...				Bioorg Med Chem Lett 25: 2041-5 (2015) Article DOI: 10.1016/j.bmcl.2015.03.095 BindingDB Entry DOI: 10.7270/Q22F7Q3D
					More data for this Ligand-Target Pair