BDBM50069767 CHEMBL3407549

SMILES: CN(CCCNC(=O)c1ccc2c(Cl)c3CCCCc3nc2c1)Cc1ccccc1

InChI Key: InChIKey=HZSMLOMFQAOLDQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50069767   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50069767 (CHEMBL3407549) Show SMILES CN(CCCNC(=O)c1ccc2c(Cl)c3CCCCc3nc2c1)Cc1ccccc1 Show InChI InChI=1S/C25H28ClN3O/c1-29(17-18-8-3-2-4-9-18)15-7-14-27-25(30)19-12-13-21-23(16-19)28-22-11-6-5-10-20(22)24(21)26/h2-4,8-9,12-13,16H,5-7,10-11,14-15,17H2,1H3,(H,27,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.81E+4	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of human USP7 by Ub-AMC assay				J Med Chem 58: 1581-95 (2015) Article DOI: 10.1021/jm501061a BindingDB Entry DOI: 10.7270/Q29025GH
					More data for this Ligand-Target Pair