BDBM50069777 (2E)-3-(4-chlorophenyl)-2-cyano-N-[2-(4-hydroxyphenyl)ethyl]acrylamide::(E)-3-(4-Chloro-phenyl)-2-cyano-N-[2-(4-hydroxy-phenyl)-ethyl]-acrylamide::CHEMBL60230

SMILES: Oc1ccc(CCNC(=O)C(=C\c2ccc(Cl)cc2)\C#N)cc1

InChI Key: InChIKey=ZOAKFIJMFNBGQH-RVDMUPIBSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50069777   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50069777 ((2E)-3-(4-chlorophenyl)-2-cyano-N-[2-(4-hydroxyphe...) Show SMILES Oc1ccc(CCNC(=O)C(=C\c2ccc(Cl)cc2)\C#N)cc1 Show InChI InChI=1S/C18H15ClN2O2/c19-16-5-1-14(2-6-16)11-15(12-20)18(23)21-10-9-13-3-7-17(22)8-4-13/h1-8,11,22H,9-10H2,(H,21,23)/b15-11+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Oregon Curated by ChEMBL					Assay Description Antagonistic activity against N-methyl-D-aspartate glutamate receptor 1/2A.				J Med Chem 42: 3412-20 (1999) Article DOI: 10.1021/jm990199u BindingDB Entry DOI: 10.7270/Q2RR1XFD
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50069777 ((2E)-3-(4-chlorophenyl)-2-cyano-N-[2-(4-hydroxyphe...) Show SMILES Oc1ccc(CCNC(=O)C(=C\c2ccc(Cl)cc2)\C#N)cc1 Show InChI InChI=1S/C18H15ClN2O2/c19-16-5-1-14(2-6-16)11-15(12-20)18(23)21-10-9-13-3-7-17(22)8-4-13/h1-8,11,22H,9-10H2,(H,21,23)/b15-11+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oregon Curated by ChEMBL					Assay Description Antagonistic activity against N-methyl-D-aspartate glutamate receptor 1/2B.				J Med Chem 42: 3412-20 (1999) Article DOI: 10.1021/jm990199u BindingDB Entry DOI: 10.7270/Q2RR1XFD
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1 (RAT-Rattus norvegicus (Rat))	BDBM50069777 ((2E)-3-(4-chlorophenyl)-2-cyano-N-[2-(4-hydroxyphe...) Show SMILES Oc1ccc(CCNC(=O)C(=C\c2ccc(Cl)cc2)\C#N)cc1 Show InChI InChI=1S/C18H15ClN2O2/c19-16-5-1-14(2-6-16)11-15(12-20)18(23)21-10-9-13-3-7-17(22)8-4-13/h1-8,11,22H,9-10H2,(H,21,23)/b15-11+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Oregon Curated by ChEMBL					Assay Description Antagonistic activity against N-methyl-D-aspartate glutamate receptor 1/2C.				J Med Chem 42: 3412-20 (1999) Article DOI: 10.1021/jm990199u BindingDB Entry DOI: 10.7270/Q2RR1XFD
					More data for this Ligand-Target Pair