BDBM50069849 CHEMBL412372::[5-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyridin-2-yl]-methanol

SMILES: CN1CCC[C@H]1COc1ccc(CO)nc1

InChI Key: InChIKey=IQFQICCQQUXBPA-NSHDSACASA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50069849   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50069849 (CHEMBL412372 | [5-((S)-1-Methyl-pyrrolidin-2-ylmet...) Show SMILES CN1CCC[C@H]1COc1ccc(CO)nc1 Show InChI InChI=1S/C12H18N2O2/c1-14-6-2-3-11(14)9-16-12-5-4-10(8-15)13-7-12/h4-5,7,11,15H,2-3,6,8-9H2,1H3/t11-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	97	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity towards nAChR (alpha4-beta2) by the displacement of [3H]-(-)-cytisine in whole rat brain membranes.				Bioorg Med Chem Lett 8: 249-54 (1999) BindingDB Entry DOI: 10.7270/Q2P26X90
					More data for this Ligand-Target Pair