BDBM50069912 CHEMBL323118::N-[5-(2-Benzylamino-ethoxy)-2-fluoro-phenyl]-methanesulfonamide

SMILES: CS(=O)(=O)Nc1cc(OCCNCc2ccccc2)ccc1F

InChI Key: InChIKey=HEHPXIHFYMLODY-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50069912   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50069912 (CHEMBL323118 | N-[5-(2-Benzylamino-ethoxy)-2-fluor...) Show SMILES CS(=O)(=O)Nc1cc(OCCNCc2ccccc2)ccc1F Show InChI InChI=1S/C16H19FN2O3S/c1-23(20,21)19-16-11-14(7-8-15(16)17)22-10-9-18-12-13-5-3-2-4-6-13/h2-8,11,18-19H,9-10,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description Agonistic activity towards dopamine D2 receptor using radioligand [3H]-quinpirole in rat striatal membranes				Bioorg Med Chem Lett 8: 295-300 (1999) BindingDB Entry DOI: 10.7270/Q28W3CG1
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50069912 (CHEMBL323118 | N-[5-(2-Benzylamino-ethoxy)-2-fluor...) Show SMILES CS(=O)(=O)Nc1cc(OCCNCc2ccccc2)ccc1F Show InChI InChI=1S/C16H19FN2O3S/c1-23(20,21)19-16-11-14(7-8-15(16)17)22-10-9-18-12-13-5-3-2-4-6-13/h2-8,11,18-19H,9-10,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description Antagonistic activity towards dopamine D2 receptor using radioligand [3H]-spiperone in rat striatal membranes				Bioorg Med Chem Lett 8: 295-300 (1999) BindingDB Entry DOI: 10.7270/Q28W3CG1
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50069912 (CHEMBL323118 | N-[5-(2-Benzylamino-ethoxy)-2-fluor...) Show SMILES CS(=O)(=O)Nc1cc(OCCNCc2ccccc2)ccc1F Show InChI InChI=1S/C16H19FN2O3S/c1-23(20,21)19-16-11-14(7-8-15(16)17)22-10-9-18-12-13-5-3-2-4-6-13/h2-8,11,18-19H,9-10,12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human cloned dopamine (hD3) receptor expressed in CHO cells using [3H]-spiperone as radioligand				Bioorg Med Chem Lett 8: 295-300 (1999) BindingDB Entry DOI: 10.7270/Q28W3CG1
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50069912 (CHEMBL323118 | N-[5-(2-Benzylamino-ethoxy)-2-fluor...) Show SMILES CS(=O)(=O)Nc1cc(OCCNCc2ccccc2)ccc1F Show InChI InChI=1S/C16H19FN2O3S/c1-23(20,21)19-16-11-14(7-8-15(16)17)22-10-9-18-12-13-5-3-2-4-6-13/h2-8,11,18-19H,9-10,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human cloned dopamine (hD2s) receptors expressed in CHO cell membranes using [3H]-spiperone				Bioorg Med Chem Lett 8: 295-300 (1999) BindingDB Entry DOI: 10.7270/Q28W3CG1
					More data for this Ligand-Target Pair