BDBM50069917 Benzyl-(2-phenoxy-ethyl)-amine::CHEMBL103951
SMILES: C(COc1ccccc1)NCc1ccccc1
InChI Key: InChIKey=XTNXLNGNJZRBRW-UHFFFAOYSA-N
Data: 5 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50069917 (Benzyl-(2-phenoxy-ethyl)-amine | CHEMBL103951) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 68 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Laboratories Curated by ChEMBL | Assay Description Agonistic activity towards dopamine D2 receptor using radioligand [3H]-quinpirole in rat striatal membranes | Bioorg Med Chem Lett 8: 295-300 (1999) BindingDB Entry DOI: 10.7270/Q28W3CG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50069917 (Benzyl-(2-phenoxy-ethyl)-amine | CHEMBL103951) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 94 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Laboratories Curated by ChEMBL | Assay Description Binding affinity towards human cloned dopamine (hD4.4) receptor expressed in CHO cells using [3H]-spiperone as radioligand | Bioorg Med Chem Lett 8: 295-300 (1999) BindingDB Entry DOI: 10.7270/Q28W3CG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50069917 (Benzyl-(2-phenoxy-ethyl)-amine | CHEMBL103951) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 241 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Laboratories Curated by ChEMBL | Assay Description Antagonistic activity towards dopamine D2 receptor using radioligand [3H]spiperone in rat striatal membranes | Bioorg Med Chem Lett 8: 295-300 (1999) BindingDB Entry DOI: 10.7270/Q28W3CG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50069917 (Benzyl-(2-phenoxy-ethyl)-amine | CHEMBL103951) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | >300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Laboratories Curated by ChEMBL | Assay Description Binding affinity towards human cloned dopamine (hD2s) receptors expressed in CHO cell membranes using [3H]-spiperone | Bioorg Med Chem Lett 8: 295-300 (1999) BindingDB Entry DOI: 10.7270/Q28W3CG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50069917 (Benzyl-(2-phenoxy-ethyl)-amine | CHEMBL103951) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | >400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Laboratories Curated by ChEMBL | Assay Description Binding affinity towards human cloned dopamine (hD3) receptor expressed in CHO cells using [3H]-spiperone as radioligand | Bioorg Med Chem Lett 8: 295-300 (1999) BindingDB Entry DOI: 10.7270/Q28W3CG1 | |||||||||||
More data for this Ligand-Target Pair |