BDBM50069918 CHEMBL99849::N-[3-(2-Benzylamino-ethoxy)-phenyl]-methanesulfonamide

SMILES: CS(=O)(=O)Nc1cccc(OCCNCc2ccccc2)c1

InChI Key: InChIKey=ZMVMIDCCNZYMFG-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50069918   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50069918 (CHEMBL99849 | N-[3-(2-Benzylamino-ethoxy)-phenyl]-...) Show SMILES CS(=O)(=O)Nc1cccc(OCCNCc2ccccc2)c1 Show InChI InChI=1S/C16H20N2O3S/c1-22(19,20)18-15-8-5-9-16(12-15)21-11-10-17-13-14-6-3-2-4-7-14/h2-9,12,17-18H,10-11,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description Agonistic activity towards dopamine D2 receptor using radioligand [3H]-quinpirole in rat striatal membranes				Bioorg Med Chem Lett 8: 295-300 (1999) BindingDB Entry DOI: 10.7270/Q28W3CG1
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50069918 (CHEMBL99849 | N-[3-(2-Benzylamino-ethoxy)-phenyl]-...) Show SMILES CS(=O)(=O)Nc1cccc(OCCNCc2ccccc2)c1 Show InChI InChI=1S/C16H20N2O3S/c1-22(19,20)18-15-8-5-9-16(12-15)21-11-10-17-13-14-6-3-2-4-7-14/h2-9,12,17-18H,10-11,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description Antagonistic activity towards dopamine D2 receptor using radioligand [3H]spiperone in rat striatal membranes				Bioorg Med Chem Lett 8: 295-300 (1999) BindingDB Entry DOI: 10.7270/Q28W3CG1
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50069918 (CHEMBL99849 | N-[3-(2-Benzylamino-ethoxy)-phenyl]-...) Show SMILES CS(=O)(=O)Nc1cccc(OCCNCc2ccccc2)c1 Show InChI InChI=1S/C16H20N2O3S/c1-22(19,20)18-15-8-5-9-16(12-15)21-11-10-17-13-14-6-3-2-4-7-14/h2-9,12,17-18H,10-11,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human cloned dopamine (hD2s) receptors expressed in CHO cell membranes using [3H]-spiperone				Bioorg Med Chem Lett 8: 295-300 (1999) BindingDB Entry DOI: 10.7270/Q28W3CG1
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50069918 (CHEMBL99849 | N-[3-(2-Benzylamino-ethoxy)-phenyl]-...) Show SMILES CS(=O)(=O)Nc1cccc(OCCNCc2ccccc2)c1 Show InChI InChI=1S/C16H20N2O3S/c1-22(19,20)18-15-8-5-9-16(12-15)21-11-10-17-13-14-6-3-2-4-7-14/h2-9,12,17-18H,10-11,13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human cloned dopamine (hD3) receptor expressed in CHO cells using [3H]-spiperone as radioligand				Bioorg Med Chem Lett 8: 295-300 (1999) BindingDB Entry DOI: 10.7270/Q28W3CG1
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50069918 (CHEMBL99849 | N-[3-(2-Benzylamino-ethoxy)-phenyl]-...) Show SMILES CS(=O)(=O)Nc1cccc(OCCNCc2ccccc2)c1 Show InChI InChI=1S/C16H20N2O3S/c1-22(19,20)18-15-8-5-9-16(12-15)21-11-10-17-13-14-6-3-2-4-7-14/h2-9,12,17-18H,10-11,13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human cloned dopamine (hD4.4) receptor expressed in CHO cells using [3H]-spiperone as radioligand				Bioorg Med Chem Lett 8: 295-300 (1999) BindingDB Entry DOI: 10.7270/Q28W3CG1
					More data for this Ligand-Target Pair