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SMILES: [O-]C(=O)c1c2CCc3nc(ccc3-c2nc2ccc(F)cc12)-c1ccccc1

InChI Key: InChIKey=WBGQYABREKQGQT-UHFFFAOYSA-M

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50069954   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dihydroorotate dehydrogenase (quinone), mitochondrial


(Homo sapiens (Human))		BDBM50069954
PNG
(CHEMBL104001 | Sodium; 9-fluoro-3-phenyl-5,6-dihyd...)
Show SMILES [O-]C(=O)c1c2CCc3nc(ccc3-c2nc2ccc(F)cc12)-c1ccccc1
Show InChI InChI=1S/C23H15FN2O2/c24-14-6-9-20-17(12-14)21(23(27)28)16-8-11-19-15(22(16)26-20)7-10-18(25-19)13-4-2-1-3-5-13/h1-7,9-10,12H,8,11H2,(H,27,28)/p-1
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PubMed
 409n/an/an/an/an/an/an/an/a



DuPont Merck Pharmaceutical Company

Curated by ChEMBL


Assay Description
Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)

Bioorg Med Chem Lett 8: 307-12 (1999)


BindingDB Entry DOI: 10.7270/Q21C1W19
More data for this
Ligand-Target Pair