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SMILES: [O-]C(=O)c1c2CCc3nc(ncc3-c2nc2ccc(F)cc12)-c1ccccc1

InChI Key: InChIKey=MVAYUOFWPROCBG-UHFFFAOYSA-M

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50069974   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dihydroorotate dehydrogenase (quinone), mitochondrial


(Homo sapiens (Human))		BDBM50069974
PNG
(CHEMBL322100 | Sodium; 9-fluoro-3-phenyl-5,6-dihyd...)
Show SMILES [O-]C(=O)c1c2CCc3nc(ncc3-c2nc2ccc(F)cc12)-c1ccccc1
Show InChI InChI=1S/C22H14FN3O2/c23-13-6-8-17-15(10-13)19(22(27)28)14-7-9-18-16(20(14)25-17)11-24-21(26-18)12-4-2-1-3-5-12/h1-6,8,10-11H,7,9H2,(H,27,28)/p-1
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PubMed
 380n/an/an/an/an/an/an/an/a



DuPont Merck Pharmaceutical Company

Curated by ChEMBL


Assay Description
Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)

Bioorg Med Chem Lett 8: 307-12 (1999)


BindingDB Entry DOI: 10.7270/Q21C1W19
More data for this
Ligand-Target Pair