BDBM50070097 (Z)-6-(4-chlorophenyl)-7-(pyridin-4-ylmethylene)-6,7-dihydroindolizin-8(5H)-one::6-(4-Chloro-phenyl)-7-[1-pyridin-4-yl-meth-(Z)-ylidene]-6,7-dihydro-5H-indolizin-8-one::CHEMBL9165::MR-20492

SMILES: Clc1ccc(cc1)C1Cn2cccc2C(=O)\C1=C/c1ccncc1

InChI Key: InChIKey=OMGJLQMHGRFTAP-ATVHPVEESA-N

Data: 1 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50070097   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50070097 ((Z)-6-(4-chlorophenyl)-7-(pyridin-4-ylmethylene)-6...) Show SMILES Clc1ccc(cc1)C1Cn2cccc2C(=O)\C1=C/c1ccncc1 Show InChI InChI=1S/C20H15ClN2O/c21-16-5-3-15(4-6-16)18-13-23-11-1-2-19(23)20(24)17(18)12-14-7-9-22-10-8-14/h1-12,18H,13H2/b17-12-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre d'Etudes et de Recherche sur le Médicament de Normandie Curated by ChEMBL					Assay Description Inhibition constant for human aromatase cytochrome P450 19A1 activity				Bioorg Med Chem Lett 8: 1041-4 (1999) BindingDB Entry DOI: 10.7270/Q2445KM7
					More data for this Ligand-Target Pair
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50070097 ((Z)-6-(4-chlorophenyl)-7-(pyridin-4-ylmethylene)-6...) Show SMILES Clc1ccc(cc1)C1Cn2cccc2C(=O)\C1=C/c1ccncc1 Show InChI InChI=1S/C20H15ClN2O/c21-16-5-3-15(4-6-16)18-13-23-11-1-2-19(23)20(24)17(18)12-14-7-9-22-10-8-14/h1-12,18H,13H2/b17-12-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Johns Hopkins University Curated by ChEMBL					Assay Description Inhibition of human placental microsome CYP19				Bioorg Med Chem Lett 20: 3050-64 (2010) Article DOI: 10.1016/j.bmcl.2010.03.113 BindingDB Entry DOI: 10.7270/Q2CJ8FFS
					More data for this Ligand-Target Pair
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50070097 ((Z)-6-(4-chlorophenyl)-7-(pyridin-4-ylmethylene)-6...) Show SMILES Clc1ccc(cc1)C1Cn2cccc2C(=O)\C1=C/c1ccncc1 Show InChI InChI=1S/C20H15ClN2O/c21-16-5-3-15(4-6-16)18-13-23-11-1-2-19(23)20(24)17(18)12-14-7-9-22-10-8-14/h1-12,18H,13H2/b17-12-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Centre d'Etudes et de Recherche sur le Médicament de Normandie Curated by ChEMBL					Assay Description Inhibition of human aromatase cytochrome P450 19A1 activity				Bioorg Med Chem Lett 8: 1041-4 (1999) BindingDB Entry DOI: 10.7270/Q2445KM7
					More data for this Ligand-Target Pair
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50070097 ((Z)-6-(4-chlorophenyl)-7-(pyridin-4-ylmethylene)-6...) Show SMILES Clc1ccc(cc1)C1Cn2cccc2C(=O)\C1=C/c1ccncc1 Show InChI InChI=1S/C20H15ClN2O/c21-16-5-3-15(4-6-16)18-13-23-11-1-2-19(23)20(24)17(18)12-14-7-9-22-10-8-14/h1-12,18H,13H2/b17-12-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
University of Botswana Curated by ChEMBL					Assay Description Inhibition of aromatase				Eur J Med Chem 46: 5237-57 (2011) Article DOI: 10.1016/j.ejmech.2011.08.042 BindingDB Entry DOI: 10.7270/Q2ZG6SNF
					More data for this Ligand-Target Pair