BDBM50070203 CHEMBL14048::N-((6aR,9S,10aR)-7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-ylmethyl)-benzamide

SMILES: CN1C[C@H](CNC(=O)c2ccccc2)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13

InChI Key: InChIKey=MJSUQPQBXGYQHP-NYSBEXSLSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50070203   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50070203 (CHEMBL14048 | N-((6aR,9S,10aR)-7-Methyl-4,6,6a,7,8...) Show SMILES CN1C[C@H](CNC(=O)c2ccccc2)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 Show InChI InChI=1S/C23H25N3O/c1-26-14-15(12-25-23(27)16-6-3-2-4-7-16)10-19-18-8-5-9-20-22(18)17(13-24-20)11-21(19)26/h2-9,13,15,19,21,24H,10-12,14H2,1H3,(H,25,27)/t15-,19+,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn S.p.A.-CNS Research Curated by ChEMBL					Assay Description Displacement of [3H]-spiroperidol from D2 receptor in rat striatum				Bioorg Med Chem Lett 8: 1117-22 (1999) BindingDB Entry DOI: 10.7270/Q2M61JF3
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50070203 (CHEMBL14048 | N-((6aR,9S,10aR)-7-Methyl-4,6,6a,7,8...) Show SMILES CN1C[C@H](CNC(=O)c2ccccc2)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 Show InChI InChI=1S/C23H25N3O/c1-26-14-15(12-25-23(27)16-6-3-2-4-7-16)10-19-18-8-5-9-20-22(18)17(13-24-20)11-21(19)26/h2-9,13,15,19,21,24H,10-12,14H2,1H3,(H,25,27)/t15-,19+,21+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn S.p.A.-CNS Research Curated by ChEMBL					Assay Description Displacement of [3H]-SCH-23,390 from D1 receptor in rat striatum				Bioorg Med Chem Lett 8: 1117-22 (1999) BindingDB Entry DOI: 10.7270/Q2M61JF3
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50070203 (CHEMBL14048 | N-((6aR,9S,10aR)-7-Methyl-4,6,6a,7,8...) Show SMILES CN1C[C@H](CNC(=O)c2ccccc2)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 Show InChI InChI=1S/C23H25N3O/c1-26-14-15(12-25-23(27)16-6-3-2-4-7-16)10-19-18-8-5-9-20-22(18)17(13-24-20)11-21(19)26/h2-9,13,15,19,21,24H,10-12,14H2,1H3,(H,25,27)/t15-,19+,21+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn S.p.A.-CNS Research Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from Alpha-1 adrenergic receptor in rat frontal cortex				Bioorg Med Chem Lett 8: 1117-22 (1999) BindingDB Entry DOI: 10.7270/Q2M61JF3
					More data for this Ligand-Target Pair
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50070203 (CHEMBL14048 | N-((6aR,9S,10aR)-7-Methyl-4,6,6a,7,8...) Show SMILES CN1C[C@H](CNC(=O)c2ccccc2)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 Show InChI InChI=1S/C23H25N3O/c1-26-14-15(12-25-23(27)16-6-3-2-4-7-16)10-19-18-8-5-9-20-22(18)17(13-24-20)11-21(19)26/h2-9,13,15,19,21,24H,10-12,14H2,1H3,(H,25,27)/t15-,19+,21+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn S.p.A.-CNS Research Curated by ChEMBL					Assay Description Displacement of [3H]yohimbine from Alpha-2 adrenergic receptor in rat frontal cortex				Bioorg Med Chem Lett 8: 1117-22 (1999) BindingDB Entry DOI: 10.7270/Q2M61JF3
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50070203 (CHEMBL14048 | N-((6aR,9S,10aR)-7-Methyl-4,6,6a,7,8...) Show SMILES CN1C[C@H](CNC(=O)c2ccccc2)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 Show InChI InChI=1S/C23H25N3O/c1-26-14-15(12-25-23(27)16-6-3-2-4-7-16)10-19-18-8-5-9-20-22(18)17(13-24-20)11-21(19)26/h2-9,13,15,19,21,24H,10-12,14H2,1H3,(H,25,27)/t15-,19+,21+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn S.p.A.-CNS Research Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat pre frontal cortex				Bioorg Med Chem Lett 8: 1117-22 (1999) BindingDB Entry DOI: 10.7270/Q2M61JF3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50070203 (CHEMBL14048 | N-((6aR,9S,10aR)-7-Methyl-4,6,6a,7,8...) Show SMILES CN1C[C@H](CNC(=O)c2ccccc2)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 Show InChI InChI=1S/C23H25N3O/c1-26-14-15(12-25-23(27)16-6-3-2-4-7-16)10-19-18-8-5-9-20-22(18)17(13-24-20)11-21(19)26/h2-9,13,15,19,21,24H,10-12,14H2,1H3,(H,25,27)/t15-,19+,21+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn S.p.A.-CNS Research Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampus				Bioorg Med Chem Lett 8: 1117-22 (1999) BindingDB Entry DOI: 10.7270/Q2M61JF3
					More data for this Ligand-Target Pair