BDBM50070494 CHEMBL36336::{(R)-1-Benzyl-2-[(R)-2-((R)-1-formyl-4-guanidino-butylcarbamoyl)-pyrrolidin-1-yl]-2-oxo-ethyl}-carbamic acid tert-butyl ester
SMILES: CC(C)(C)OC(=O)N[C@H](Cc1ccccc1)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CCCNC(N)=N)C=O
InChI Key: InChIKey=JDXUSWQJCGTBLN-VAMGGRTRSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prothrombin (Homo sapiens (Human)) | BDBM50070494 (CHEMBL36336 | {(R)-1-Benzyl-2-[(R)-2-((R)-1-formyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Drug Research Curated by ChEMBL | Assay Description Ability to inhibit Thrombin was evaluated by amidolytic method using fluorogenic or chromogenic substrates | Bioorg Med Chem Lett 8: 1477-82 (1999) Checked by Author BindingDB Entry DOI: 10.7270/Q2GB24KF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-1 (Homo sapiens (Human)) | BDBM50070494 (CHEMBL36336 | {(R)-1-Benzyl-2-[(R)-2-((R)-1-formyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.79E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Drug Research Curated by ChEMBL | Assay Description Ability to inhibit Trypsin was evaluated by amidolytic method using fluorogenic or chromogenic substrates | Bioorg Med Chem Lett 8: 1477-82 (1999) Checked by Author BindingDB Entry DOI: 10.7270/Q2GB24KF | |||||||||||
More data for this Ligand-Target Pair |