BDBM50070590 CHEMBL3408819

SMILES: CCCCCCCCn1c2CCN(Cc2c2cc(ccc12)-c1ccc(cc1)S(C)(=O)=O)C(N)=O

InChI Key: InChIKey=LPYJYQRRFJCWMT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50070590   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human))	BDBM50070590 (CHEMBL3408819) Show SMILES CCCCCCCCn1c2CCN(Cc2c2cc(ccc12)-c1ccc(cc1)S(C)(=O)=O)C(N)=O Show InChI InChI=1S/C27H35N3O3S/c1-3-4-5-6-7-8-16-30-25-14-11-21(20-9-12-22(13-10-20)34(2,32)33)18-23(25)24-19-29(27(28)31)17-15-26(24)30/h9-14,18H,3-8,15-17,19H2,1-2H3,(H2,28,31)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
National University of Singapore Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT2 assessed as deacetylation of N-acetyl lysine residue in p53 (317 to 320) after 30 mins by luciferase-mediated l...				Eur J Med Chem 92: 145-55 (2015) Article DOI: 10.1016/j.ejmech.2014.12.027 BindingDB Entry DOI: 10.7270/Q270834V
					More data for this Ligand-Target Pair
NAD-Dependent Deacetylase Sirtuin-1 (Homo sapiens (Human))	BDBM50070590 (CHEMBL3408819) Show SMILES CCCCCCCCn1c2CCN(Cc2c2cc(ccc12)-c1ccc(cc1)S(C)(=O)=O)C(N)=O Show InChI InChI=1S/C27H35N3O3S/c1-3-4-5-6-7-8-16-30-25-14-11-21(20-9-12-22(13-10-20)34(2,32)33)18-23(25)24-19-29(27(28)31)17-15-26(24)30/h9-14,18H,3-8,15-17,19H2,1-2H3,(H2,28,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
National University of Singapore Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT1 assessed as deacetylation of N-acetyl lysine residue in p53 (317 to 320) after 30 mins by luciferase-mediated l...				Eur J Med Chem 92: 145-55 (2015) Article DOI: 10.1016/j.ejmech.2014.12.027 BindingDB Entry DOI: 10.7270/Q270834V
					More data for this Ligand-Target Pair