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SMILES: CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)c1cc(O)ccc1O)C(=O)N[C@@H](CC)C(O)=O

InChI Key: InChIKey=PSWZXOFIRFJZCW-ORRMCWHZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50070701   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prothrombin


(Homo sapiens (Human))		BDBM50070701
PNG
(CHEMBL2372661 | Nazumamide A (NAZA) analogue)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)c1cc(O)ccc1O)C(=O)N[C@@H](CC)C(O)=O
Show InChI InChI=1S/C33H41N5O8/c1-4-18(3)28(31(43)35-23(5-2)33(45)46)37-30(42)26-11-8-14-38(26)32(44)25(15-19-17-34-24-10-7-6-9-21(19)24)36-29(41)22-16-20(39)12-13-27(22)40/h6-7,9-10,12-13,16-18,23,25-26,28,34,39-40H,4-5,8,11,14-15H2,1-3H3,(H,35,43)(H,36,41)(H,37,42)(H,45,46)/t18?,23?,25-,26-,28-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.71E+6n/an/an/an/a8.3n/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Anti-thrombin activity by competitive enzyme assay using the fluorogenic substrate Tos-Gly-Pro-Arg-AMC at pH 8.3.

Bioorg Med Chem Lett 8: 1669-72 (1999)


BindingDB Entry DOI: 10.7270/Q2G73CV8
More data for this
Ligand-Target Pair