BDBM50070721 CHEMBL2372692::CHEMBL295218::Nazumamide A (NAZA) analogue

SMILES: CC[C@H](C)[C@H](NC(=O)[C@@H]1CC(O)CN1C(=O)[C@H](CCCCN)NC(=O)c1cc(O)ccc1O)C(=O)N[C@@H](CC)C(O)=O

InChI Key: InChIKey=HDNLFEQJBKXRNC-KXGDRSMUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50070721   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50070721 (CHEMBL2372692 | Nazumamide A (NAZA) analogue) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CC(O)CN1C(=O)[C@H](CCCCN)NC(=O)c1cc(O)ccc1O)C(=O)N[C@@H](CC)C(O)=O Show InChI InChI=1S/C28H43N5O9/c1-4-15(3)23(26(39)30-19(5-2)28(41)42)32-25(38)21-13-17(35)14-33(21)27(40)20(8-6-7-11-29)31-24(37)18-12-16(34)9-10-22(18)36/h9-10,12,15,17,19-21,23,34-36H,4-8,11,13-14,29H2,1-3H3,(H,30,39)(H,31,37)(H,32,38)(H,41,42)/t15?,17?,19?,20-,21-,23-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.98E+5	n/a	n/a	n/a	n/a	8.3	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Anti-thrombin activity by competitive enzyme assay using the fluorogenic substrate Tos-Gly-Pro-Arg-AMC at pH 8.3.				Bioorg Med Chem Lett 8: 1669-72 (1999) BindingDB Entry DOI: 10.7270/Q2G73CV8
					More data for this Ligand-Target Pair