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SMILES: CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)c1cc(O)ccc1O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC)C(O)=O

InChI Key: InChIKey=YKKQKXOFTRUMHD-LDJGGQOZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50070738   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prothrombin


(Homo sapiens (Human))		BDBM50070738
PNG
(CHEMBL2372702 | Nazumamide A (NAZA) analogue)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)c1cc(O)ccc1O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC)C(O)=O
Show InChI InChI=1S/C28H45N5O8S/c1-5-16(3)23(27(39)32-21(12-14-42-4)25(37)30-19(6-2)28(40)41)33-26(38)20(9-7-8-13-29)31-24(36)18-15-17(34)10-11-22(18)35/h10-11,15-16,19-21,23,34-35H,5-9,12-14,29H2,1-4H3,(H,30,37)(H,31,36)(H,32,39)(H,33,38)(H,40,41)/t16?,19?,20-,21-,23-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 4.60E+4n/an/an/an/a8.3n/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Anti-thrombin activity by competitive enzyme assay using the fluorogenic substrate Tos-Gly-Pro-Arg-AMC at pH 8.3.

Bioorg Med Chem Lett 8: 1669-72 (1999)


BindingDB Entry DOI: 10.7270/Q2G73CV8
More data for this
Ligand-Target Pair