BDBM50071017 CHEMBL3409737

SMILES: CC1CCN(CC1)c1nc2c(CCC2(F)F)c(Nc2cc([nH]n2)C2CC2)n1

InChI Key: InChIKey=UVYDUWGGZVXKRB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071017   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor I receptor (Homo sapiens (Human))	BDBM50071017 (CHEMBL3409737) Show SMILES CC1CCN(CC1)c1nc2c(CCC2(F)F)c(Nc2cc([nH]n2)C2CC2)n1 Show InChI InChI=1S/C19H24F2N6/c1-11-5-8-27(9-6-11)18-23-16-13(4-7-19(16,20)21)17(24-18)22-15-10-14(25-26-15)12-2-3-12/h10-12H,2-9H2,1H3,(H2,22,23,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	786	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Enterprises Limited Curated by ChEMBL					Assay Description Inhibition of IGF1R (unknown origin) using poly-G1 as substrate incubated for 10 mins prior to substrate addition measured after 1 hr by time-resolve...				Eur J Med Chem 92: 246-56 (2015) Article DOI: 10.1016/j.ejmech.2014.12.053 BindingDB Entry DOI: 10.7270/Q2639RFV
					More data for this Ligand-Target Pair