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BDBM50071018 CHEMBL3409736

SMILES: CC1CCN(CC1)c1nc2C3CCC(C3)c2c(Nc2cc([nH]n2)C2CC2)n1

InChI Key: InChIKey=QSUHURPPIZAGGT-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071018   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Insulin-like growth factor I receptor


(Homo sapiens (Human))
BDBM50071018
PNG
(CHEMBL3409736)
Show SMILES CC1CCN(CC1)c1nc2C3CCC(C3)c2c(Nc2cc([nH]n2)C2CC2)n1 |THB:16:15:11.12:14|
Show InChI InChI=1S/C21H28N6/c1-12-6-8-27(9-7-12)21-23-19-15-5-4-14(10-15)18(19)20(24-21)22-17-11-16(25-26-17)13-2-3-13/h11-15H,2-10H2,1H3,(H2,22,23,24,25,26)
PDB
MMDB

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Article
PubMed
n/an/a 1.19E+3n/an/an/an/an/an/a



Piramal Enterprises Limited

Curated by ChEMBL


Assay Description
Inhibition of IGF1R (unknown origin) using poly-G1 as substrate incubated for 10 mins prior to substrate addition measured after 1 hr by time-resolve...


Eur J Med Chem 92: 246-56 (2015)


Article DOI: 10.1016/j.ejmech.2014.12.053
BindingDB Entry DOI: 10.7270/Q2639RFV
More data for this
Ligand-Target Pair