BDBM50071027 CHEMBL3409727

SMILES: C1Cc2nc(nc(Nc3cc([nH]n3)-c3ccccc3)c2C1)N1CCCCCC1

InChI Key: InChIKey=QXOLJHUEQFNGSO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071027   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor I receptor (Homo sapiens (Human))	BDBM50071027 (CHEMBL3409727) Show SMILES C1Cc2nc(nc(Nc3cc([nH]n3)-c3ccccc3)c2C1)N1CCCCCC1 Show InChI InChI=1S/C22H26N6/c1-2-7-14-28(13-6-1)22-23-18-12-8-11-17(18)21(25-22)24-20-15-19(26-27-20)16-9-4-3-5-10-16/h3-5,9-10,15H,1-2,6-8,11-14H2,(H2,23,24,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Enterprises Limited Curated by ChEMBL					Assay Description Inhibition of IGF1R (unknown origin) using poly-G1 as substrate incubated for 10 mins prior to substrate addition measured after 1 hr by time-resolve...				Eur J Med Chem 92: 246-56 (2015) Article DOI: 10.1016/j.ejmech.2014.12.053 BindingDB Entry DOI: 10.7270/Q2639RFV
					More data for this Ligand-Target Pair