BDBM50071029 CHEMBL3409725

SMILES: Cc1ccc(CNc2nc3CCCc3c(Nc3cc([nH]n3)C3CC3)n2)cc1

InChI Key: InChIKey=NOTLKYGBHLVVQZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071029   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor I receptor (Homo sapiens (Human))	BDBM50071029 (CHEMBL3409725) Show SMILES Cc1ccc(CNc2nc3CCCc3c(Nc3cc([nH]n3)C3CC3)n2)cc1 Show InChI InChI=1S/C21H24N6/c1-13-5-7-14(8-6-13)12-22-21-23-17-4-2-3-16(17)20(25-21)24-19-11-18(26-27-19)15-9-10-15/h5-8,11,15H,2-4,9-10,12H2,1H3,(H3,22,23,24,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	149	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Enterprises Limited Curated by ChEMBL					Assay Description Inhibition of IGF1R (unknown origin) using poly-G1 as substrate incubated for 10 mins prior to substrate addition measured after 1 hr by time-resolve...				Eur J Med Chem 92: 246-56 (2015) Article DOI: 10.1016/j.ejmech.2014.12.053 BindingDB Entry DOI: 10.7270/Q2639RFV
					More data for this Ligand-Target Pair