BDBM50071030 CHEMBL3409724

SMILES: C(Nc1nc2CCCc2c(Nc2cc([nH]n2)C2CC2)n1)c1ccccc1

InChI Key: InChIKey=APPSICVVQOQHSJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071030   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor I receptor (Homo sapiens (Human))	BDBM50071030 (CHEMBL3409724) Show SMILES C(Nc1nc2CCCc2c(Nc2cc([nH]n2)C2CC2)n1)c1ccccc1 Show InChI InChI=1S/C20H22N6/c1-2-5-13(6-3-1)12-21-20-22-16-8-4-7-15(16)19(24-20)23-18-11-17(25-26-18)14-9-10-14/h1-3,5-6,11,14H,4,7-10,12H2,(H3,21,22,23,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	267	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Enterprises Limited Curated by ChEMBL					Assay Description Inhibition of IGF1R (unknown origin) using poly-G1 as substrate incubated for 10 mins prior to substrate addition measured after 1 hr by time-resolve...				Eur J Med Chem 92: 246-56 (2015) Article DOI: 10.1016/j.ejmech.2014.12.053 BindingDB Entry DOI: 10.7270/Q2639RFV
					More data for this Ligand-Target Pair