BDBM50071034 CHEMBL3409720

SMILES: OC(=O)C1CCN(CC1)c1nc2CCCc2c(Nc2cc([nH]n2)C2CC2)n1

InChI Key: InChIKey=QBWJJYNNPLRCON-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071034   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor I receptor (Homo sapiens (Human))	BDBM50071034 (CHEMBL3409720) Show SMILES OC(=O)C1CCN(CC1)c1nc2CCCc2c(Nc2cc([nH]n2)C2CC2)n1 Show InChI InChI=1S/C19H24N6O2/c26-18(27)12-6-8-25(9-7-12)19-20-14-3-1-2-13(14)17(22-19)21-16-10-15(23-24-16)11-4-5-11/h10-12H,1-9H2,(H,26,27)(H2,20,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Enterprises Limited Curated by ChEMBL					Assay Description Inhibition of IGF1R (unknown origin) using poly-G1 as substrate incubated for 10 mins prior to substrate addition measured after 1 hr by time-resolve...				Eur J Med Chem 92: 246-56 (2015) Article DOI: 10.1016/j.ejmech.2014.12.053 BindingDB Entry DOI: 10.7270/Q2639RFV
					More data for this Ligand-Target Pair