BDBM50071038 CHEMBL3409715

SMILES: CCN(CC)C(=O)C1CCCN(C1)c1nc2CCCc2c(Nc2cc([nH]n2)C2CC2)n1

InChI Key: InChIKey=XHFYVJBFWUNXPK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071038   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor I receptor (Homo sapiens (Human))	BDBM50071038 (CHEMBL3409715) Show SMILES CCN(CC)C(=O)C1CCCN(C1)c1nc2CCCc2c(Nc2cc([nH]n2)C2CC2)n1 Show InChI InChI=1S/C23H33N7O/c1-3-29(4-2)22(31)16-7-6-12-30(14-16)23-24-18-9-5-8-17(18)21(26-23)25-20-13-19(27-28-20)15-10-11-15/h13,15-16H,3-12,14H2,1-2H3,(H2,24,25,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	184	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Enterprises Limited Curated by ChEMBL					Assay Description Inhibition of IGF1R (unknown origin) using poly-G1 as substrate incubated for 10 mins prior to substrate addition measured after 1 hr by time-resolve...				Eur J Med Chem 92: 246-56 (2015) Article DOI: 10.1016/j.ejmech.2014.12.053 BindingDB Entry DOI: 10.7270/Q2639RFV
					More data for this Ligand-Target Pair