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BDBM50071122 CHEMBL417940::N-[2-(3,4-Dichloro-phenyl)-4-(4-propionyl-piperidin-1-yl)-butyl]-N-methyl-benzamide

SMILES: CCC(=O)C1CCN(CCC(CN(C)C(=O)c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1

InChI Key: InChIKey=FDCLRKXPPRFSKU-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071122   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neurokinin 2 receptor


(Homo sapiens (Human))		BDBM50071122
PNG
(CHEMBL417940 | N-[2-(3,4-Dichloro-phenyl)-4-(4-pro...)
Show SMILES CCC(=O)C1CCN(CCC(CN(C)C(=O)c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1
Show InChI InChI=1S/C26H32Cl2N2O2/c1-3-25(31)19-11-14-30(15-12-19)16-13-22(21-9-10-23(27)24(28)17-21)18-29(2)26(32)20-7-5-4-6-8-20/h4-10,17,19,22H,3,11-16,18H2,1-2H3
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PubMed
 9.20n/an/an/an/an/an/an/an/a



ZENECA Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells

Bioorg Med Chem Lett 8: 1935-40 (1999)


BindingDB Entry DOI: 10.7270/Q2J38RPQ
More data for this
Ligand-Target Pair