BDBM50071835 4-Benzoyl-1-(4-methoxy-benzenesulfonyl)-[1,4]diazepane-2-carboxylic acid hydroxyamide::4-benzoyl-N-hydroxy-1-(4-methoxyphenylsulfonyl)-1,4-diazepane-2-carboxamide::CHEMBL327621

SMILES: COc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)C(=O)c1ccccc1

InChI Key: InChIKey=KPJZJSWNHXZALM-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50071835   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM50071835 (4-Benzoyl-1-(4-methoxy-benzenesulfonyl)-[1,4]diaze...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)C(=O)c1ccccc1 Show InChI InChI=1S/C20H23N3O6S/c1-29-16-8-10-17(11-9-16)30(27,28)23-13-5-12-22(14-18(23)19(24)21-26)20(25)15-6-3-2-4-7-15/h2-4,6-11,18,26H,5,12-14H2,1H3,(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-13 (MMP-13)				Bioorg Med Chem Lett 8: 2657-62 (1999) BindingDB Entry DOI: 10.7270/Q28K79KZ
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50071835 (4-Benzoyl-1-(4-methoxy-benzenesulfonyl)-[1,4]diaze...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)C(=O)c1ccccc1 Show InChI InChI=1S/C20H23N3O6S/c1-29-16-8-10-17(11-9-16)30(27,28)23-13-5-12-22(14-18(23)19(24)21-26)20(25)15-6-3-2-4-7-15/h2-4,6-11,18,26H,5,12-14H2,1H3,(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Pomona College Curated by ChEMBL					Assay Description Inhibition of MMP13				Bioorg Med Chem 15: 2223-68 (2007) Article DOI: 10.1016/j.bmc.2007.01.011 BindingDB Entry DOI: 10.7270/Q2571DBD
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50071835 (4-Benzoyl-1-(4-methoxy-benzenesulfonyl)-[1,4]diaze...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)C(=O)c1ccccc1 Show InChI InChI=1S/C20H23N3O6S/c1-29-16-8-10-17(11-9-16)30(27,28)23-13-5-12-22(14-18(23)19(24)21-26)20(25)15-6-3-2-4-7-15/h2-4,6-11,18,26H,5,12-14H2,1H3,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-1 (MMP-1)				Bioorg Med Chem Lett 8: 2657-62 (1999) BindingDB Entry DOI: 10.7270/Q28K79KZ
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50071835 (4-Benzoyl-1-(4-methoxy-benzenesulfonyl)-[1,4]diaze...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)C(=O)c1ccccc1 Show InChI InChI=1S/C20H23N3O6S/c1-29-16-8-10-17(11-9-16)30(27,28)23-13-5-12-22(14-18(23)19(24)21-26)20(25)15-6-3-2-4-7-15/h2-4,6-11,18,26H,5,12-14H2,1H3,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-9 (MMP-9)				Bioorg Med Chem Lett 8: 2657-62 (1999) BindingDB Entry DOI: 10.7270/Q28K79KZ
					More data for this Ligand-Target Pair