BDBM50071841 4-(Biphenyl-2-carbonyl)-1-(4-methoxy-benzenesulfonyl)-[1,4]diazepane-2-carboxylic acid hydroxyamide::CHEMBL327442

SMILES: COc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)C(=O)c1ccccc1-c1ccccc1

InChI Key: InChIKey=RWPUCYUUOPJZLU-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50071841   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Homo sapiens (Human))	BDBM50071841 (4-(Biphenyl-2-carbonyl)-1-(4-methoxy-benzenesulfon...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)C(=O)c1ccccc1-c1ccccc1 Show InChI InChI=1S/C26H27N3O6S/c1-35-20-12-14-21(15-13-20)36(33,34)29-17-7-16-28(18-24(29)25(30)27-32)26(31)23-11-6-5-10-22(23)19-8-3-2-4-9-19/h2-6,8-15,24,32H,7,16-18H2,1H3,(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	116	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-1 (MMP-1)				Bioorg Med Chem Lett 8: 2657-62 (1999) BindingDB Entry DOI: 10.7270/Q28K79KZ
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50071841 (4-(Biphenyl-2-carbonyl)-1-(4-methoxy-benzenesulfon...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)C(=O)c1ccccc1-c1ccccc1 Show InChI InChI=1S/C26H27N3O6S/c1-35-20-12-14-21(15-13-20)36(33,34)29-17-7-16-28(18-24(29)25(30)27-32)26(31)23-11-6-5-10-22(23)19-8-3-2-4-9-19/h2-6,8-15,24,32H,7,16-18H2,1H3,(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Pomona College Curated by ChEMBL					Assay Description Inhibition of MMP13				Bioorg Med Chem 15: 2223-68 (2007) Article DOI: 10.1016/j.bmc.2007.01.011 BindingDB Entry DOI: 10.7270/Q2571DBD
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50071841 (4-(Biphenyl-2-carbonyl)-1-(4-methoxy-benzenesulfon...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)C(=O)c1ccccc1-c1ccccc1 Show InChI InChI=1S/C26H27N3O6S/c1-35-20-12-14-21(15-13-20)36(33,34)29-17-7-16-28(18-24(29)25(30)27-32)26(31)23-11-6-5-10-22(23)19-8-3-2-4-9-19/h2-6,8-15,24,32H,7,16-18H2,1H3,(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-9 (MMP-9)				Bioorg Med Chem Lett 8: 2657-62 (1999) BindingDB Entry DOI: 10.7270/Q28K79KZ
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50071841 (4-(Biphenyl-2-carbonyl)-1-(4-methoxy-benzenesulfon...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)C(=O)c1ccccc1-c1ccccc1 Show InChI InChI=1S/C26H27N3O6S/c1-35-20-12-14-21(15-13-20)36(33,34)29-17-7-16-28(18-24(29)25(30)27-32)26(31)23-11-6-5-10-22(23)19-8-3-2-4-9-19/h2-6,8-15,24,32H,7,16-18H2,1H3,(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-13 (MMP-13)				Bioorg Med Chem Lett 8: 2657-62 (1999) BindingDB Entry DOI: 10.7270/Q28K79KZ
					More data for this Ligand-Target Pair