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SMILES: FC(F)(F)c1nc2c(cccc2[nH]1)N1CCN(Cc2ccccc2)CC1

InChI Key: InChIKey=PSWUORNVMIRUSW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50071855   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50071855 (4-(4-Benzyl-piperazin-1-yl)-2-trifluoromethyl-1H-b...) Show SMILES FC(F)(F)c1nc2c(cccc2[nH]1)N1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C19H19F3N4/c20-19(21,22)18-23-15-7-4-8-16(17(15)24-18)26-11-9-25(10-12-26)13-14-5-2-1-3-6-14/h1-8H,9-13H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratory Curated by ChEMBL					Assay Description Affinity for Dopamine receptor D2 in rat striatal membranes for high agonist state using [3H]-quinpirole				Bioorg Med Chem Lett 8: 2675-80 (1999) BindingDB Entry DOI: 10.7270/Q2C53K0X
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50071855 (4-(4-Benzyl-piperazin-1-yl)-2-trifluoromethyl-1H-b...) Show SMILES FC(F)(F)c1nc2c(cccc2[nH]1)N1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C19H19F3N4/c20-19(21,22)18-23-15-7-4-8-16(17(15)24-18)26-11-9-25(10-12-26)13-14-5-2-1-3-6-14/h1-8H,9-13H2,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratory Curated by ChEMBL					Assay Description Affinity towards human Dopamine receptor D4.4 expressed in CHO cells using [3H]-spiperone				Bioorg Med Chem Lett 8: 2675-80 (1999) BindingDB Entry DOI: 10.7270/Q2C53K0X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50071855 (4-(4-Benzyl-piperazin-1-yl)-2-trifluoromethyl-1H-b...) Show SMILES FC(F)(F)c1nc2c(cccc2[nH]1)N1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C19H19F3N4/c20-19(21,22)18-23-15-7-4-8-16(17(15)24-18)26-11-9-25(10-12-26)13-14-5-2-1-3-6-14/h1-8H,9-13H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratory Curated by ChEMBL					Assay Description Affinity of compound for the Dopamine receptor D2 in rat striatal membranes was determined for low agonist state in rat striatal membranes using [3H]...				Bioorg Med Chem Lett 8: 2675-80 (1999) BindingDB Entry DOI: 10.7270/Q2C53K0X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50071855 (4-(4-Benzyl-piperazin-1-yl)-2-trifluoromethyl-1H-b...) Show SMILES FC(F)(F)c1nc2c(cccc2[nH]1)N1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C19H19F3N4/c20-19(21,22)18-23-15-7-4-8-16(17(15)24-18)26-11-9-25(10-12-26)13-14-5-2-1-3-6-14/h1-8H,9-13H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratory Curated by ChEMBL					Assay Description Affinity towards human Dopamine receptor D2 expressed in CHO cells using [3H]-spiperone				Bioorg Med Chem Lett 8: 2675-80 (1999) BindingDB Entry DOI: 10.7270/Q2C53K0X
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50071855 (4-(4-Benzyl-piperazin-1-yl)-2-trifluoromethyl-1H-b...) Show SMILES FC(F)(F)c1nc2c(cccc2[nH]1)N1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C19H19F3N4/c20-19(21,22)18-23-15-7-4-8-16(17(15)24-18)26-11-9-25(10-12-26)13-14-5-2-1-3-6-14/h1-8H,9-13H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratory Curated by ChEMBL					Assay Description Affinity towards human Dopamine receptor D3 expressed in CHO cells using [3H]-spiperone				Bioorg Med Chem Lett 8: 2675-80 (1999) BindingDB Entry DOI: 10.7270/Q2C53K0X
					More data for this Ligand-Target Pair