BDBM50072001 11-Ethyl-1,3,3-trimethyl-4,11-dihydro-3H-pyrido[3,2-a]carbazole::CHEMBL91858

SMILES: CCn1c2ccccc2c2ccc3NC(C)(C)C=C(C)c3c12

InChI Key: InChIKey=XIEIFFBKPGJSCW-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072001   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50072001 (11-Ethyl-1,3,3-trimethyl-4,11-dihydro-3H-pyrido[3,...) Show SMILES CCn1c2ccccc2c2ccc3NC(C)(C)C=C(C)c3c12 |t:18| Show InChI InChI=1S/C20H22N2/c1-5-22-17-9-7-6-8-14(17)15-10-11-16-18(19(15)22)13(2)12-20(3,4)21-16/h6-12,21H,5H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	169	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity against human progesterone receptor-A (hPR-A)				Bioorg Med Chem Lett 8: 2731-6 (1999) BindingDB Entry DOI: 10.7270/Q2QF8S1M
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50072001 (11-Ethyl-1,3,3-trimethyl-4,11-dihydro-3H-pyrido[3,...) Show SMILES CCn1c2ccccc2c2ccc3NC(C)(C)C=C(C)c3c12 |t:18| Show InChI InChI=1S/C20H22N2/c1-5-22-17-9-7-6-8-14(17)15-10-11-16-18(19(15)22)13(2)12-20(3,4)21-16/h6-12,21H,5H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scientific Computing Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]progesterone from Progesterone receptor				J Med Chem 49: 4261-8 (2006) Article DOI: 10.1021/jm060234e BindingDB Entry DOI: 10.7270/Q2V69NB6
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50072001 (11-Ethyl-1,3,3-trimethyl-4,11-dihydro-3H-pyrido[3,...) Show SMILES CCn1c2ccccc2c2ccc3NC(C)(C)C=C(C)c3c12 |t:18| Show InChI InChI=1S/C20H22N2/c1-5-22-17-9-7-6-8-14(17)15-10-11-16-18(19(15)22)13(2)12-20(3,4)21-16/h6-12,21H,5H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	284	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity against human progesterone receptor-A (hPR-A)				Bioorg Med Chem Lett 8: 2731-6 (1999) BindingDB Entry DOI: 10.7270/Q2QF8S1M
					More data for this Ligand-Target Pair