null

SMILES: CC1=CC(C)(C)Nc2cc3c(-c4ccc(F)cc4C3(C)O)c(F)c12

InChI Key: InChIKey=UMKJOSHCVCLMKI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072017   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50072017 (5,8-Difluoro-2,2,4,10-tetramethyl-2,10-dihydro-1H-...) Show SMILES CC1=CC(C)(C)Nc2cc3c(-c4ccc(F)cc4C3(C)O)c(F)c12 |t:1| Show InChI InChI=1S/C20H19F2NO/c1-10-9-19(2,3)23-15-8-14-17(18(22)16(10)15)12-6-5-11(21)7-13(12)20(14,4)24/h5-9,23-24H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity against human progesterone receptor-A (hPR-A)				Bioorg Med Chem Lett 8: 2731-6 (1999) BindingDB Entry DOI: 10.7270/Q2QF8S1M
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50072017 (5,8-Difluoro-2,2,4,10-tetramethyl-2,10-dihydro-1H-...) Show SMILES CC1=CC(C)(C)Nc2cc3c(-c4ccc(F)cc4C3(C)O)c(F)c12 |t:1| Show InChI InChI=1S/C20H19F2NO/c1-10-9-19(2,3)23-15-8-14-17(18(22)16(10)15)12-6-5-11(21)7-13(12)20(14,4)24/h5-9,23-24H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity against human progesterone receptor-A (hPR-A)				Bioorg Med Chem Lett 8: 2731-6 (1999) BindingDB Entry DOI: 10.7270/Q2QF8S1M
					More data for this Ligand-Target Pair