BDBM50072069 CHEMBL3215346::CHEMBL384874::Sialyl Lewis X analogue
SMILES: CCOCCOCCOCCOCCOCCO[C@@H]1O[C@@H](CO)[C@@H](O[C@@H]2O[C@@H](CO)[C@H](O)[C@H](O[C@@]3(C[C@@H](O)[C@@H](NC(C)=O)[C@@H](O3)[C@H](O)[C@H](O)CO)C(O)=O)[C@@H]2O)[C@H](O[C@@H]2O[C@@H](C)[C@@H](O)[C@H](O)[C@@H]2O)[C@@H]1NC(C)=O
InChI Key: InChIKey=YECBVAFOBYDCKU-DCSXAZQXSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Selectin E (Rattus norvegicus) | BDBM50072069 (CHEMBL3215346 | Sialyl Lewis X analogue) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Drug Delivery System Institute, Ltd. Curated by ChEMBL | Assay Description Inhibitory concentration against Selectin E expressed at the inflammatory lesion was measured by inhibition of leukocyte rolling in the inflammatory ... | Bioorg Med Chem Lett 8: 2783-6 (1999) BindingDB Entry DOI: 10.7270/Q2B56HX1 | |||||||||||
More data for this Ligand-Target Pair |