null

SMILES: Nc1ccccc1SC(=N)C(C#N)C(C#N)c1nc2ccccc2s1

InChI Key: InChIKey=HWOMLSHWUKFYHI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072165   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity mitogen-activated protein kinase kinase 1 (Homo sapiens (Human))	BDBM50072165 (2-[1-Amino-1-(2-amino-phenylsulfanyl)-meth-(Z)-yli...) Show SMILES Nc1ccccc1SC(=N)C(C#N)C(C#N)c1nc2ccccc2s1 Show InChI InChI=1S/C18H13N5S2/c19-9-11(17(22)24-15-7-3-1-5-13(15)21)12(10-20)18-23-14-6-2-4-8-16(14)25-18/h1-8,11-12,22H,21H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Non-competitive inhibition of the dual specificity kinase MEK				Bioorg Med Chem Lett 8: 2839-44 (1999) BindingDB Entry DOI: 10.7270/Q2MW2HNN
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1/2 (Homo sapiens (Human))	BDBM50072165 (2-[1-Amino-1-(2-amino-phenylsulfanyl)-meth-(Z)-yli...) Show SMILES Nc1ccccc1SC(=N)C(C#N)C(C#N)c1nc2ccccc2s1 Show InChI InChI=1S/C18H13N5S2/c19-9-11(17(22)24-15-7-3-1-5-13(15)21)12(10-20)18-23-14-6-2-4-8-16(14)25-18/h1-8,11-12,22H,21H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Ability to antagonise AP-1 transcriptional activity				Bioorg Med Chem Lett 8: 2839-44 (1999) BindingDB Entry DOI: 10.7270/Q2MW2HNN
					More data for this Ligand-Target Pair