null

SMILES: COc1cc2c(nc(nc2cc1OCCO)N1CCOCC1)-c1cc(OCC2CC2)cc(OCC2CC2)c1

InChI Key: InChIKey=MVGFOISECUJJPH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072208   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (RAT)	BDBM50072208 (2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-6-methoxy...) Show SMILES COc1cc2c(nc(nc2cc1OCCO)N1CCOCC1)-c1cc(OCC2CC2)cc(OCC2CC2)c1 Show InChI InChI=1S/C29H35N3O6/c1-34-26-15-24-25(16-27(26)36-11-8-33)30-29(32-6-9-35-10-7-32)31-28(24)21-12-22(37-17-19-2-3-19)14-23(13-21)38-18-20-4-5-20/h12-16,19-20,33H,2-11,17-18H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Evaluated for its ability to inhibit PDE4B.				Bioorg Med Chem Lett 8: 2891-6 (1999) BindingDB Entry DOI: 10.7270/Q2PG1QVX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50072208 (2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-6-methoxy...) Show SMILES COc1cc2c(nc(nc2cc1OCCO)N1CCOCC1)-c1cc(OCC2CC2)cc(OCC2CC2)c1 Show InChI InChI=1S/C29H35N3O6/c1-34-26-15-24-25(16-27(26)36-11-8-33)30-29(32-6-9-35-10-7-32)31-28(24)21-12-22(37-17-19-2-3-19)14-23(13-21)38-18-20-4-5-20/h12-16,19-20,33H,2-11,17-18H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Evaluated for its ability to inhibit PDE4D.				Bioorg Med Chem Lett 8: 2891-6 (1999) BindingDB Entry DOI: 10.7270/Q2PG1QVX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50072208 (2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-6-methoxy...) Show SMILES COc1cc2c(nc(nc2cc1OCCO)N1CCOCC1)-c1cc(OCC2CC2)cc(OCC2CC2)c1 Show InChI InChI=1S/C29H35N3O6/c1-34-26-15-24-25(16-27(26)36-11-8-33)30-29(32-6-9-35-10-7-32)31-28(24)21-12-22(37-17-19-2-3-19)14-23(13-21)38-18-20-4-5-20/h12-16,19-20,33H,2-11,17-18H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Evaluated for its ability to inhibit PDE4A.				Bioorg Med Chem Lett 8: 2891-6 (1999) BindingDB Entry DOI: 10.7270/Q2PG1QVX
					More data for this Ligand-Target Pair