null

SMILES: CCc1nc(-c2cc(OCC3CC3)cc(OCC3CC3)c2)c2cc(OC)c(O)cc2n1

InChI Key: InChIKey=BIMKWTXBXDRUEQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072210   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50072210 (4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethyl-6-me...) Show SMILES CCc1nc(-c2cc(OCC3CC3)cc(OCC3CC3)c2)c2cc(OC)c(O)cc2n1 Show InChI InChI=1S/C25H28N2O4/c1-3-24-26-21-12-22(28)23(29-2)11-20(21)25(27-24)17-8-18(30-13-15-4-5-15)10-19(9-17)31-14-16-6-7-16/h8-12,15-16,28H,3-7,13-14H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Evaluated for its ability to inhibit PDE4A.				Bioorg Med Chem Lett 8: 2891-6 (1999) BindingDB Entry DOI: 10.7270/Q2PG1QVX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (RAT)	BDBM50072210 (4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethyl-6-me...) Show SMILES CCc1nc(-c2cc(OCC3CC3)cc(OCC3CC3)c2)c2cc(OC)c(O)cc2n1 Show InChI InChI=1S/C25H28N2O4/c1-3-24-26-21-12-22(28)23(29-2)11-20(21)25(27-24)17-8-18(30-13-15-4-5-15)10-19(9-17)31-14-16-6-7-16/h8-12,15-16,28H,3-7,13-14H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Evaluated for its ability to inhibit PDE4B.				Bioorg Med Chem Lett 8: 2891-6 (1999) BindingDB Entry DOI: 10.7270/Q2PG1QVX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50072210 (4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethyl-6-me...) Show SMILES CCc1nc(-c2cc(OCC3CC3)cc(OCC3CC3)c2)c2cc(OC)c(O)cc2n1 Show InChI InChI=1S/C25H28N2O4/c1-3-24-26-21-12-22(28)23(29-2)11-20(21)25(27-24)17-8-18(30-13-15-4-5-15)10-19(9-17)31-14-16-6-7-16/h8-12,15-16,28H,3-7,13-14H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Evaluated for its ability to inhibit PDE4D.				Bioorg Med Chem Lett 8: 2891-6 (1999) BindingDB Entry DOI: 10.7270/Q2PG1QVX
					More data for this Ligand-Target Pair