BDBM50072232 CHEMBL3408311

SMILES: CC(C)Cn1c2cc(ccc2n(C)c1=O)C(=O)c1cnn(C)c1O

InChI Key: InChIKey=VVLDTYYNTJCATH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50072232   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50072232 (CHEMBL3408311) Show SMILES CC(C)Cn1c2cc(ccc2n(C)c1=O)C(=O)c1cnn(C)c1O Show InChI InChI=1S/C17H20N4O3/c1-10(2)9-21-14-7-11(5-6-13(14)19(3)17(21)24)15(22)12-8-18-20(4)16(12)23/h5-8,10,23H,9H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis				Eur J Med Chem 92: 427-38 (2015) Article DOI: 10.1016/j.ejmech.2015.01.018 BindingDB Entry DOI: 10.7270/Q20C4XFX
					More data for this Ligand-Target Pair