BDBM50072235 CHEMBL3408312

SMILES: Cn1ncc(C(=O)c2ccc3n(C)c(=O)n(C4CCCC4)c3c2)c1O

InChI Key: InChIKey=NHPJESKIFWYVAZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50072235   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50072235 (CHEMBL3408312) Show SMILES Cn1ncc(C(=O)c2ccc3n(C)c(=O)n(C4CCCC4)c3c2)c1O Show InChI InChI=1S/C18H20N4O3/c1-20-14-8-7-11(16(23)13-10-19-21(2)17(13)24)9-15(14)22(18(20)25)12-5-3-4-6-12/h7-10,12,24H,3-6H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis				Eur J Med Chem 92: 427-38 (2015) Article DOI: 10.1016/j.ejmech.2015.01.018 BindingDB Entry DOI: 10.7270/Q20C4XFX
					More data for this Ligand-Target Pair