BDBM50072271 CHEMBL3408326

SMILES: CCCn1c2ccc(cc2n(c1=O)C(C)(C)C)C(=O)c1cnn(C)c1O

InChI Key: InChIKey=IQUAXSVTVCVTAD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50072271   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50072271 (CHEMBL3408326) Show SMILES CCCn1c2ccc(cc2n(c1=O)C(C)(C)C)C(=O)c1cnn(C)c1O Show InChI InChI=1S/C19H24N4O3/c1-6-9-22-14-8-7-12(16(24)13-11-20-21(5)17(13)25)10-15(14)23(18(22)26)19(2,3)4/h7-8,10-11,25H,6,9H2,1-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis				Eur J Med Chem 92: 427-38 (2015) Article DOI: 10.1016/j.ejmech.2015.01.018 BindingDB Entry DOI: 10.7270/Q20C4XFX
					More data for this Ligand-Target Pair