BDBM50072823 7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-4-oxo-4H-chromene-3-carbaldehyde::CHEMBL149412

SMILES: Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc3c(c2)occ(C=O)c3=O)CC1

InChI Key: InChIKey=KXQSQOALQLSOII-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072823   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50072823 (7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...) Show SMILES Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc3c(c2)occ(C=O)c3=O)CC1 Show InChI InChI=1S/C25H23FN2O5/c26-18-2-4-20-23(12-18)33-27-24(20)16-6-9-28(10-7-16)8-1-11-31-19-3-5-21-22(13-19)32-15-17(14-29)25(21)30/h2-5,12-16H,1,6-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13.1	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Grupo Ferrer Curated by ChEMBL					Assay Description Inhibition of [3H]-methylspiperone binding to rat striatal membrane Dopamine receptor D2				J Med Chem 41: 5402-9 (1999) Article DOI: 10.1021/jm9810396 BindingDB Entry DOI: 10.7270/Q2QC02N8
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50072823 (7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...) Show SMILES Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc3c(c2)occ(C=O)c3=O)CC1 Show InChI InChI=1S/C25H23FN2O5/c26-18-2-4-20-23(12-18)33-27-24(20)16-6-9-28(10-7-16)8-1-11-31-19-3-5-21-22(13-19)32-15-17(14-29)25(21)30/h2-5,12-16H,1,6-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Grupo Ferrer Curated by ChEMBL					Assay Description Inhibition of [3H]-ketanserin binding to rat frontal cortex membrane 5-hydroxytryptamine 2A receptor				J Med Chem 41: 5402-9 (1999) Article DOI: 10.1021/jm9810396 BindingDB Entry DOI: 10.7270/Q2QC02N8
					More data for this Ligand-Target Pair