BDBM50072959 CHEMBL3410535
SMILES: [O-][N+](=O)c1ccc(\C=C2/CS(=O)(=O)C\C(=C/c3ccc(cc3)[N+]([O-])=O)C2=O)cc1
InChI Key: InChIKey=SSAMIOWVUGBIJK-KAVGSWPWSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ubiquitin carboxyl-terminal hydrolase isozyme L5 (Homo sapiens (Human)) | BDBM50072959 (CHEMBL3410535) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Trieste Curated by ChEMBL | Assay Description Inhibition of GST-tagged UCHL5 (unknown origin) using Ub-AMC as substrate preincubated for 30 mins before substrate addition measured after 60 mins b... | J Med Chem 58: 1691-704 (2015) Article DOI: 10.1021/jm501336h BindingDB Entry DOI: 10.7270/Q2J67JM0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ubl carboxyl-terminal hydrolase 18 (Homo sapiens (Human)) | BDBM50072959 (CHEMBL3410535) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Trieste Curated by ChEMBL | Assay Description Inhibition of recombinant human USP18 (16 to 372 aa) expressed in Sf9 cells using ISG15-AMC as substrate preincubated for 30 mins before substrate ad... | J Med Chem 58: 1691-704 (2015) Article DOI: 10.1021/jm501336h BindingDB Entry DOI: 10.7270/Q2J67JM0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ubiquitin carboxyl-terminal hydrolase 2 (Homo sapiens (Human)) | BDBM50072959 (CHEMBL3410535) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Trieste Curated by ChEMBL | Assay Description Inhibition of USP2 catalytic domain (unknown origin) expressed in bacteria using Ub-AMC as substrate preincubated for 30 mins before substrate additi... | J Med Chem 58: 1691-704 (2015) Article DOI: 10.1021/jm501336h BindingDB Entry DOI: 10.7270/Q2J67JM0 | |||||||||||
More data for this Ligand-Target Pair |