BDBM50073733 (R)-(1-Isothiocyanatoethyl)Benzene::CHEMBL2151314
SMILES: C[C@@H](N=C=S)c1ccccc1
InChI Key: InChIKey=QQCJPTVZIZVKEZ-MRVPVSSYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Macrophage migration inhibitory factor (MIF) (Homo sapiens (Human)) | BDBM50073733 ((R)-(1-Isothiocyanatoethyl)Benzene | CHEMBL2151314) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Otago Curated by ChEMBL | Assay Description Inhibition of macrophage migration inhibitory factor tautomerase activity in human Jurkat T cells using L-dopachrome methyl ester as substrate incuba... | Eur J Med Chem 93: 501-10 (2015) Article DOI: 10.1016/j.ejmech.2015.02.012 BindingDB Entry DOI: 10.7270/Q26Q1ZZ7 | |||||||||||
More data for this Ligand-Target Pair |